DPD simulations on morphologies and structures of blank PLGA-<i>b</i>-PEG-<i>b</i>-PLGA polymeric micelles and docetaxel-loaded PLGA-<i>b</i>-PEG-<i>b</i>-PLGA polymeric micelles
Mengyao Wang, Lin Ye, Jianxu Gao, Dongmei Liu
Abstract
Dissipative particle dynamics simulation was used to study the morphologies and structures of blank (no drug) poly(lactic- co -glycolic acid)- b -poly(ethylene glycol)- b -poly(lactic- co -glycolic acid) polymeric micelles and the docetaxel-loaded polymeric micelles.
Topics & Concepts
PLGAMicellePEG ratioChemistryMaterials scienceChemical engineeringNanoparticleNanotechnologyOrganic chemistryAqueous solutionEngineeringEconomicsFinanceAdvanced Polymer Synthesis and CharacterizationPolymer Surface Interaction StudiesNanoparticle-Based Drug Delivery