C(sp<sup>2</sup>)-CF<sub>3</sub> Reductive Elimination from Well-Defined Argentate(III) Complexes [<i>n</i>Bu<sub>4</sub>N][Ag(Ar)(CF<sub>3</sub>)<sub>3</sub>]
Zehai Lu, Shihan Liu, Yu Lan, Xuebing Leng, Qilong Shen
Abstract
The preparation of a series of well-defined, shelf-stable square planar aryl(tris(trifluoromethyl))argentate(III) complexes [nBu4N]+[Ag(Ar)(CF3)3]− and their C(sp2)-CF3 bond-forming reductive elimination are described. Mechanistic studies of the C(sp2)-CF3 reductive elimination from these complexes, including kinetic studies, effect of temperature and solvent, and DFT calculations, indicate that the C(sp2)-CF3 bond-forming process occurred via a concerted reductive elimination pathway.
Topics & Concepts
Reductive eliminationChemistryTrifluoromethylArylReductive dechlorinationMedicinal chemistryStereochemistryCatalysisOrganic chemistryBiodegradationAlkylFluorine in Organic ChemistryCatalytic Cross-Coupling ReactionsInorganic Fluorides and Related Compounds