Analysis of the binding selectivity and inhibiting mechanism of chlorogenic acid isomers and their interaction with grass carp endogenous lipase using multi-spectroscopic, inhibition kinetics and modeling methods
Zeru Xu, Qiongju Cao, Anne Manyande, Shanbai Xiong, Hongying Du
Topics & Concepts
LipaseChlorogenic acidChemistrySelectivityPolyphenolIC50Hydrophobic effectKineticsMolecular dynamicsEnzymeStereochemistryBiochemistryChromatographyComputational chemistryCatalysisIn vitroAntioxidantPhysicsQuantum mechanicsProtein Interaction Studies and Fluorescence AnalysisEnzyme Catalysis and ImmobilizationAnalytical Chemistry and Chromatography