Alginate oligosaccharides improve germ cell development and testicular microenvironment to rescue busulfan disrupted spermatogenesis
Yong Zhao, Pengfei Zhang, Wei Ge, Yanni Feng, Lan Li, Zhongyi Sun, Hongfu Zhang, Wei Shen
Abstract
: AOS could be used to improve fertility in patients undergoing chemotherapy and to combat other factors that induce infertility in humans.
Topics & Concepts
SpermatogenesisGerm cellCell biologyBusulfanRescue therapyGermBiologyChemistryInternal medicineMedicineStem cellEndocrinologyBiochemistryHematopoietic stem cell transplantationGeneSperm and Testicular FunctionReproductive Biology and FertilityReproductive System and Pregnancy