Iron oxide-EDTA nanoparticles for chelation-enhanced chemodynamic therapy and ion interference therapy
Changxiao Chen, Meng Qi, Zhendong Liu, Sainan Liu, Weifang Tong, Baichao An, Binbin Ding, Ping’an Ma, Jun Lin
Abstract
experiments show that the nano chelating drugs exhibit significant improvement in Fenton reaction performance and excellent anti-tumor activity. This study based on chelation provides a new idea for designing efficient catalysts to enhance the Fenton reaction and provides more revelations on future research on CDT.
Topics & Concepts
ChelationFenton reactionChemistryNanomedicineReactive oxygen speciesRadicalHydroxyl radicalCatalysisIn vitroBiophysicsNanoparticleCombinatorial chemistryPhotochemistryNuclear chemistryInorganic chemistryBiochemistryNanotechnologyMaterials scienceBiologyNanoplatforms for cancer theranosticsLanthanide and Transition Metal ComplexesNanoparticle-Based Drug Delivery