Allosteric modulation of GPCRs: From structural insights to in silico drug discovery
Margherita Persechino, Janik B. Hedderich, Peter Kolb, Daniel Hilger
Topics & Concepts
Allosteric regulationDrug discoveryG protein-coupled receptorIn silicoComputational biologyAllosteric enzymeAllosteric modulatorSmall moleculeFunction (biology)BiologyChemistryReceptorBioinformaticsBiochemistryCell biologyGeneReceptor Mechanisms and SignalingNeuropeptides and Animal PhysiologyChemical Synthesis and Analysis