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Design and synthesis of 2-(2-isonicotinoylhydrazineylidene)propanamides as InhA inhibitors with high antitubercular activity

Václav Pflégr, Lilla Borbála Horváth, Jiřina Stolaříková, Adrian Pál, Jana Korduláková, Szilvia Bősze, Jarmila Vinšová, Martin Krátký

2021European Journal of Medicinal Chemistry26 citationsDOI

Topics & Concepts

INHAChemistryIsoniazidMycobacterium tuberculosisLipophilicityAntimycobacterialStereochemistryBiochemistryTuberculosisPathologyMedicineTuberculosis Research and EpidemiologySynthesis and biological activityCancer therapeutics and mechanisms
Design and synthesis of 2-(2-isonicotinoylhydrazineylidene)propanamides as InhA inhibitors with high antitubercular activity | Litcius