Discovery of novel deoxyvasicinone derivatives with benzenesulfonamide substituents as multifunctional agents against Alzheimer's disease
Shuanghong Dong, Jucheng Xia, Fang Wang, Lili Yang, Siqi Xing, Jiyu Du, Tingting Zhang, Zeng Li
Topics & Concepts
ChemistryNeuroprotectionIn vivoPharmacologyAcetylcholinesteraseOxidative stressAchéIntracellularReactive oxygen speciesBiochemistryEnzymeMedicineBiotechnologyBiologyCholinesterase and Neurodegenerative DiseasesAlzheimer's disease research and treatmentsComputational Drug Discovery Methods