S1P/S1PR1 axis promotes macrophage M1 polarization through NLRP3 inflammasome activation in Lupus nephritis
Jihua Tian, Sijia Chang, Jing Wang, Jingshu Chen, Huanyu Xu, Taiping Huang, Juanjuan Wang, Jing Kang, Weiping Fan, Yanhong Wang, Weiping Fan, Yanhong Wang
Topics & Concepts
Lupus nephritisMacrophage polarizationS1PR1ImmunologyInflammasomeMedicineSystemic lupus erythematosusInflammationMacrophagePathogenesisNephritisReceptorCancer researchBiologyInternal medicineIn vitroVEGF receptorsVascular endothelial growth factorDiseaseVascular endothelial growth factor ABiochemistryInflammasome and immune disordersSphingolipid Metabolism and SignalingSystemic Lupus Erythematosus Research