Positive association between severity of COVID-19 infection and liver damage: a systematic review and meta-analysis.
Hajar Shokri‐Afra, Nasrin Amiri‐Dashatan, Fatemeh Ghorbani, Iradj Maleki, Mostafa Rezaei–Tavirani
Abstract
AIM: The current study aimed to report a pooled analysis of the association of the circulating levels of liver enzymes and total bilirubin with severe and non-severe COVID-19. BACKGROUND: The ongoing coronavirus outbreak is an important threat to health worldwide. Epidemiological data representing greater risk of liver failure in patients infected with Severe Acute Respiratory Syndrome Coronavirus-2 (SARS-CoV-2). METHODS: statistics. Sensitivity analysis was also evaluated. RESULTS: < 0.05] with severe COVID-19 infection than in females. CONCLUSION: The alterations of liver function indexes caused by SARS-CoV-2 infection suggested a potential prognosis biomarker for screening of severe patients at early stages of the disease.