Litcius/Paper detail

Icariside II potentiates the anti-PD-1 antitumor effect by reducing chemotactic infiltration of myeloid-derived suppressor cells into the tumor microenvironment via ROS-mediated inactivation of the SRC/ERK/STAT3 signaling pathways

Qing Kong, Mengyu Ma, Li Zhang, Suqing Liu, Shan He, Jinfeng Wu, Baojun Liu, Jingcheng Dong

2022Phytomedicine26 citationsDOI

Topics & Concepts

Cancer researchChemokineTumor microenvironmentChemistryMAPK/ERK pathwayLewis lung carcinomaImmune systemCXCL2PharmacologySignal transductionCancerBiologyChemokine receptorImmunologyMedicineMetastasisBiochemistryInternal medicineTumor cellsMedicinal Plant Pharmacodynamics ResearchImmune cells in cancerImmune Cell Function and Interaction