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MALAT1-mediated recruitment of the histone methyltransferase EZH2 to the microRNA-22 promoter leads to cardiomyocyte apoptosis in diabetic cardiomyopathy

Chong Wang, Guibo Liu, Heran Yang, Sufen Guo, Hongwei Wang, Zhihui Dong, Xinxin Li, Yuxin Bai, Yongxia Cheng

2020The Science of The Total Environment61 citationsDOI

Topics & Concepts

Diabetic cardiomyopathyPathogenesisApoptosisCardiomyopathyCancer researchMedicineEZH2Diabetes mellitusInternal medicineBiologyEndocrinologyEpigeneticsHeart failureGeneGeneticsCancer-related molecular mechanisms researchRNA modifications and cancerCancer-related gene regulation
MALAT1-mediated recruitment of the histone methyltransferase EZH2 to the microRNA-22 promoter leads to cardiomyocyte apoptosis in diabetic cardiomyopathy | Litcius