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Photoinduced Catalyst-Free Deuterodefunctionalization of Aryltriazenes with CDCl<sub>3</sub>

Bin Wang, Yang Shao, Ziren Chen, Yu Xia, Fei Xue, Weiwei Jin, Shaofeng Wu, Yonghong Zhang, Chenjiang Liu

2024Organic Letters23 citationsDOI

Abstract

A photoinduced deuterodetriazenation of aryltriazenes with CDCl 3 under catalyst-free conditions is reported. The reactions featured simple operation, ecofriendly conditions, readily available reagents, inexpensive D sources, precise site selectivity, and a wide range of substrates. Since aryltriazenes could be readily synthesized from arylamine, this protocol can be used as a general method for easily and accurately incorporating deuterium into aromatic systems by using CDCl 3 as a D source.

Topics & Concepts

ChemistryCatalysisReagentCombinatorial chemistrySelectivityDeuteriumOrganic chemistryQuantum mechanicsPhysicsChemical Reactions and IsotopesFluorine in Organic ChemistryRadical Photochemical Reactions