Constitutive Hepatic mTORC1 Activation Aggravates Alcohol-Induced Liver Injury via Endoplasmic Reticulum Stress–Mediated Ferroptosis
Lin Xu, Yuanyuan Zhao, Yang Yang, Enbo Qi, Boao Liu, Peili Zhuang, Shiyi Song, Tingmin Chang, Zhiguo Chen, Xiaohong Kang, Xiwen Xiong
Topics & Concepts
Endoplasmic reticulummTORC1MedicineLiver injuryUnfolded protein responseAlcoholChemistryCell biologyEndocrinologyInternal medicineBiologyBiochemistrySignal transductionPI3K/AKT/mTOR pathwayFerroptosis and cancer prognosisEndoplasmic Reticulum Stress and DiseaseAlcohol Consumption and Health Effects