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Ni-Catalyzed stereoselective difunctionalization of alkynes

Wenfeng Liu, Wangqing Kong

2020Organic Chemistry Frontiers158 citationsDOIOpen Access PDF

Abstract

We summarize the progress of the nickel-catalyzed alkyne difunctionalization reaction for the synthesis of tri- and tetrasubstituted olefins, with an emphasis on the strategy and control of stereochemistry.

Topics & Concepts

ChemistryStereoselectivityAlkyneCatalysisCombinatorial chemistryNickelOrganic chemistryCatalytic Alkyne ReactionsCatalytic C–H Functionalization MethodsCatalytic Cross-Coupling Reactions
Ni-Catalyzed stereoselective difunctionalization of alkynes | Litcius