Aptamers: an emerging navigation tool of therapeutic agents for targeted cancer therapy
Chang Yang, Yu Jiang, Sai Heng Hao, Xing Yan, De Fei Hong, Hua Naranmandura
Abstract
In this review, we comprehensively discuss the current advances in the screening approaches of aptamers targeting cancer specific biomarkers and development of the aptamer–drug conjugate strategy.
Topics & Concepts
AptamerTargeted therapyDrugCancerTargeted drug deliveryCancer therapyDrug deliveryComputational biologyMedicinePharmacologyBiologyNanotechnologyMaterials scienceInternal medicineGeneticsAdvanced biosensing and bioanalysis techniquesRNA Interference and Gene DeliveryRNA and protein synthesis mechanisms