Enantiodivergent biosynthesis of β-hydroxy esters by self-sufficient heterogeneous biocatalysts in a continuous flow
Daniel Andrés‐Sanz, Ainhoa Maiz-Iginitz, Juan M. Bolívar, Alejandro H. Orrego, Haritz Sardón, Fernando López‐Gallego
Abstract
Developing two self-sufficient heterogeneous biocatalysts to synthesise enantiopure β-hydroxy esters in continuous flow. Operational conditions are tuned to maximise the productivity and stability of biocatalytic packed-bed reactors.
Topics & Concepts
Enantiopure drugFlow chemistryChemistryFlow (mathematics)Continuous flowProductivityStability (learning theory)Biochemical engineeringOrganic chemistryCatalysisComputer scienceEnantioselective synthesisMathematicsEngineeringMacroeconomicsEconomicsGeometryMachine learningInnovative Microfluidic and Catalytic Techniques InnovationEnzyme Catalysis and ImmobilizationMicrobial Metabolic Engineering and Bioproduction