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Sensitization of hepatocellular carcinoma cells towards doxorubicin and sorafenib is facilitated by glucose-dependent alterations in reactive oxygen species, P-glycoprotein and DKK4

Surbhi Chouhan, Snahlata Singh, Dipti Athavale, Pranay Ramteke, Muralidharan Vanuopadath, Bipin G. Nair, Sudarslal Sadasivan Nair, Manoj Kumar Bhat

2020Journal of Biosciences29 citationsDOI

Topics & Concepts

Hepatocellular carcinomaDoxorubicinSorafenibCancer researchIntracellularReactive oxygen speciesChemistryCancer cellCell cultureP-glycoproteinCell biologyBiologyBiochemistryCancerMultiple drug resistanceAntibioticsGeneticsChemotherapyDrug Transport and Resistance MechanismsMetabolism, Diabetes, and CancerCancer, Hypoxia, and Metabolism
Sensitization of hepatocellular carcinoma cells towards doxorubicin and sorafenib is facilitated by glucose-dependent alterations in reactive oxygen species, P-glycoprotein and DKK4 | Litcius