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Targeting cyclin-dependent kinase 2 CDK2: Insights from molecular docking and dynamics simulation – A systematic computational approach to discover novel cancer therapeutics

Bharath Kumar Chagaleti, Shantha Kumar B., Anjana G.V., Rajakrishnan Rajagopal, Ahmed Alfarhan, Jesu Arockiaraj, Kathiravan Muthu Kumaradoss, S. Karthick Raja Namasivayam

2024Computational Biology and Chemistry67 citationsDOI

Topics & Concepts

Docking (animal)PharmacophoreMolecular dynamicsChemistryComputational chemistryBinding affinitiesCombinatorial chemistryLigand (biochemistry)Computational biologyStereochemistryBiochemistryBiologyReceptorMedicineNursingComputational Drug Discovery MethodsAdvanced Breast Cancer TherapiesCancer therapeutics and mechanisms
Targeting cyclin-dependent kinase 2 CDK2: Insights from molecular docking and dynamics simulation – A systematic computational approach to discover novel cancer therapeutics | Litcius