MiR-223-3p attenuates M1 macrophage polarization via suppressing the Notch signaling pathway and NLRP3-mediated pyroptosis in experimental autoimmune uveitis
Ruyi Qu, Yuan Peng, Mengxian Zhou, Shuqin Xu, Xuewei Yin, Yan Qiu, Bin Liu, Yane Gao, Hongsheng Bi, Dadong Guo
Topics & Concepts
PyroptosisUveitisMacrophage polarizationNotch signaling pathwayImmunologyInflammasomePathogenesisSignal transductionAutoimmunityCell biologyInflammationMedicineCancer researchBiologyChemistryMacrophageImmune systemBiochemistryIn vitroInflammasome and immune disordersOcular Diseases and Behçet’s Syndromeinterferon and immune responses