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Sodium fluoride activates the extrinsic apoptosis via regulating NOX4/ROS-mediated p53/DR5 signaling pathway in lung cells both in vitro and in vivo

Chao Song, Dongmei Shi, Kaiwen Chang, Xianghui Li, Qing Dong, Xia Ma, Xuefei Wang, Zhenhuan Guo, Yonglu Liu, Jundong Wang

2021Free Radical Biology and Medicine30 citationsDOI

Topics & Concepts

NOX4ApoptosisSodium fluorideChemistryNicotinamide adenine dinucleotide phosphateNADPH oxidaseReactive oxygen speciesCaspaseGene knockdownCell biologyCancer researchProgrammed cell deathBiologyOxidase testFluorideBiochemistryEnzymeInorganic chemistryFluoride Effects and RemovalNeutrophil, Myeloperoxidase and Oxidative MechanismsInflammation biomarkers and pathways
Sodium fluoride activates the extrinsic apoptosis via regulating NOX4/ROS-mediated p53/DR5 signaling pathway in lung cells both in vitro and in vivo | Litcius