A Designed, Highly Efficient Pyrrolysyl-tRNA Synthetase Mutant Binds o-Chlorophenylalanine Using Two Halogen Bonds
Erol C. Vatansever, Kai S. Yang, Zhi Geng, Yuchen Qiao, Pingwei Li, Shiqing Xu, Wenshe Ray Liu
Topics & Concepts
Amino acidGenetic codeMutantTransfer RNAActive siteChemistryAminoacyl tRNA synthetaseStereochemistryLigand (biochemistry)BiochemistryEnzymeRNAGeneReceptorRNA and protein synthesis mechanismsGenomics and Phylogenetic StudiesRNA modifications and cancer