Metastatic cutaneous apocrine adenocarcinoma successfully treated with systemic anti‐androgen therapy—A case report
Fanny Collette, Marc Hamoir, Pascal Van Eeckhout, P. Dabadie, Thierry Duprez, Sandra Schmitz, Jean‐Pascal Machiels
Abstract
Primary cutaneous apocrine adenocarcinoma (PCAC) is an extremely rare neoplasm involving the sweat glands. Due to a lack of cases, there is no consensus for the systemic treatment of locally advanced or metastatic PCAC. Anti-androgen therapy may have activity in inoperable or metastatic PCAC with high androgen receptor (AR) expression.
Topics & Concepts
MedicineApocrineSystemic therapyAndrogen receptorAdenocarcinomaAndrogenSweat glandMetastatic adenocarcinomaOncologyInternal medicinePathologyDermatologyCancerSWEATHormoneBreast cancerProstate cancerCancer and Skin LesionsSoft tissue tumor case studiesBreast Lesions and Carcinomas