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Case Report: Carfilzomib-induced Thrombotic Microangiopathy With Complement Activation Treated Successfully With Eculizumab

Divaya Bhutani, Amer Assal, Markus Y. Mapara, Samantha Prinzing, Suzanne Lentzsch

2020Clinical Lymphoma Myeloma & Leukemia23 citationsDOI

Topics & Concepts

Thrombotic microangiopathyEculizumabComplement systemADAMTS13Thrombotic thrombocytopenic purpuraAtypical hemolytic uremic syndromeMedicineComplement component 5ImmunologyComplement factor BAlternative complement pathwayShiga toxinHemolytic anemiaVon Willebrand factorCoagulopathyInternal medicinePlateletAntibodyBiologyGeneVirulenceBiochemistryDiseaseComplement system in diseasesRenal Diseases and GlomerulopathiesRenal Transplantation Outcomes and Treatments
Case Report: Carfilzomib-induced Thrombotic Microangiopathy With Complement Activation Treated Successfully With Eculizumab | Litcius