CAF-secreted LOX promotes PD-L1 expression via histone Lactylation and regulates tumor EMT through TGFβ/IGF1 signaling in gastric Cancer
Zedong Li, Panping Liang, Zhengwen Chen, Zehua Chen, Tao Jin, Fengjun He, Xiaolong Chen, Kun Yang
Topics & Concepts
Transforming growth factorSignal transductionCancerCancer researchTumor microenvironmentHistoneCell biologyBiologyTumor cellsGeneGeneticsInflammatory mediators and NSAID effectsImmune cells in cancerAngiogenesis and VEGF in Cancer