Nanoassembly of doxorubicin-conjugated polyphosphoester and siRNA simultaneously elicited macrophage- and T cell- mediated anticancer immune response for cancer therapy
Dongdong Li, Ziyang Cao, Chaoran Chen, Hengyi Li, Shan He, Xurui Hou, Mingtao Liang, Xianzhu Yang, Jun Wang
Topics & Concepts
DoxorubicinImmune systemCancer researchMacrophageCancer cellImmunotherapyCancer immunotherapyT cellCytotoxic T cellImmunogenic cell deathCancerCellImmunologyMedicineBiologyChemotherapyIn vitroInternal medicineBiochemistryGeneticsImmune cells in cancerNanoplatforms for cancer theranosticsPhagocytosis and Immune Regulation