Maternal electronic cigarette use during pregnancy affects long-term arterial function in offspring
Eiman Aboaziza, Kimberly Feaster, Lance Hare, Paul D. Chantler, I. Mark Olfert
Abstract
We observe a significant alteration in arterial structure and function in adolescent and adult offspring due to developmental exposure to toxicants resulting from perinatal maternal vaping. Taken together with previous work that described lasting dysfunction in cerebral microvasculature in offspring, these data underscore the adverse consequences of maternal exposure to electronic cigarette aerosol in conduit and resistance vessels alike, irrespective of nicotine content.
Topics & Concepts
OffspringElectronic cigaretteNicotinePregnancyPhysiologyMedicineInternal medicineBiologyPathologyGeneticsAir Quality and Health ImpactsBirth, Development, and HealthSmoking Behavior and Cessation