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MiR-221-3p-mediated downregulation of MDM2 reverses the paclitaxel resistance of non-small cell lung cancer in vitro and in vivo

Liwei Ni, Jianhao Xu, Fenglun Zhao, Xiaoxiao Dai, Jialong Tao, Jie Pan, Aiming Shi, Zhu Shen, Cunjin Su, Yusong Zhang

2021European Journal of Pharmacology28 citationsDOI

Topics & Concepts

PaclitaxelMdm2A549 cellmicroRNACancer researchDownregulation and upregulationLung cancerIn vivoCell cultureBiologyCancerDrug resistanceMedicineOncologyGeneBiochemistryGeneticsMicrobiologyBiotechnologyMicroRNA in disease regulationCancer-related molecular mechanisms researchRNA modifications and cancer
MiR-221-3p-mediated downregulation of MDM2 reverses the paclitaxel resistance of non-small cell lung cancer in vitro and in vivo | Litcius