Biosynthesis of Sesquiterpenes in Basidiomycetes: A Review
Jiajun Wu, Xiaoran Yang, Yingce Duan, Pengchao Wang, Jianzhao Qi, Jin‐Ming Gao, Chengwei Liu
Abstract
Sesquiterpenes are common small-molecule natural products with a wide range of promising applications and are biosynthesized by sesquiterpene synthase (STS). Basidiomycetes are valuable and important biological resources. To date, hundreds of related sesquiterpenoids have been discovered in basidiomycetes, and the biosynthetic pathways of some of these compounds have been elucidated. This review summarizes 122 STSs and 2 fusion enzymes STSs identified from 26 species of basidiomycetes over the past 20 years. The biological functions of enzymes and compound structures are described, and related research is discussed.
Topics & Concepts
SesquiterpeneBiologyBiosynthesisEnzymeBiochemistryComputational biologyBotanyFungal Biology and ApplicationsPlant biochemistry and biosynthesisMicrobial Natural Products and Biosynthesis