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Lycopene mitigates paclitaxel-induced cognitive impairment in mice; Insights into Nrf2/HO-1, NF-κB/NLRP3, and GRP-78/ATF-6 axes

Nasriah Zakaria, Esther T. Menze, Doaa A. Elsherbiny, Mariane G. Tadros, Mina Y. George

2025Progress in Neuro-Psychopharmacology and Biological Psychiatry12 citationsDOI

Topics & Concepts

PaclitaxelLycopeneCognitive impairmentPharmacologyNF-κBChemistryCognitionMedicineCancer researchInternal medicineAntioxidantBiochemistrySignal transductionChemotherapyPsychiatryGenomics, phytochemicals, and oxidative stressTryptophan and brain disordersNeuroinflammation and Neurodegeneration Mechanisms
Lycopene mitigates paclitaxel-induced cognitive impairment in mice; Insights into Nrf2/HO-1, NF-κB/NLRP3, and GRP-78/ATF-6 axes | Litcius