Electrochemical Behavior and Voltammetric Determination of Chloramphenicol and Doxycycline Using a Glassy Carbon Electrode Modified with Single‐walled Carbon Nanohorns
Shuang Han, Xuan Zhang, Hongda Sun, Jinping Wei, Hui Wang, Shuangyu Wang, Jing Jin, Zhichao Zhang
Abstract
Abstract We report a method for the direct and quantitative determination of chloramphenicol (CAP) and doxycycline (DOX) using a glassy carbon electrode (GCE) modified with carboxylic‐group‐functionalized single‐walled carbon nanohorns. The modified electrode exhibits high electrocatalytic activity towards the reduction of CAP and the oxidation of DOX. It shows a linear response to CAP between 0.1 μM and 100 μM and to DOX between 0.5 μM and 100 μM. The detection limits for CAP and DOX are 0.1 μM and 0.5 μM, respectively. The modified GCE displays good sensitivity, making it suitable for the determination of CAP and DOX in real samples.
Topics & Concepts
ElectrochemistryElectrodeGlassy carbonMaterials scienceCarbon fibersChloramphenicolDoxycyclineNuclear chemistryChemistryCyclic voltammetryAntibioticsComposite materialComposite numberPhysical chemistryBiochemistryElectrochemical sensors and biosensorsElectrochemical Analysis and ApplicationsAnalytical Chemistry and Sensors