Exosomal O-GlcNAc transferase from esophageal carcinoma stem cell promotes cancer immunosuppression through up-regulation of PD-1 in CD8+ T cells
Yunfeng Yuan, Lin Wang, Di Ge, Lijie Tan, Benjin Cao, Hong Fan, Liang Xue
Topics & Concepts
CD8Cancer researchCancer stem cellStem cellCytotoxic T cellBiologyCarcinogenesisExosomeMetastasisMicrovesiclesChemistryMolecular biologyCancerImmune systemImmunologyCell biologyBiochemistrymicroRNAIn vitroGeneticsGeneExtracellular vesicles in diseaseGalectins and Cancer BiologyImmunotherapy and Immune Responses