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Inverse-Designed Aid Lenses for Precise Correction of Color Vision Deficiency

Ye Tian, Hanchuan Tang, Tianyu Kang, Xinyi Guo, Jiaxin Wang, Jianfeng Zang

2022Nano Letters23 citationsDOI

Abstract

Color vision deficiency (CVD) is a common ocular disorder affecting more than 300 million people on the earth. Although no clinical cure for the disorder currently exists, some specialized color filtering glasses/lenses based on dyes, metasurfaces, or nanocomposites have been employed for CVD management. However, as CVD patients usually diversify in their classification and severity, none of the current lenses provides a customized correction for various CVD patients, resulting in undesirable correction effects. Here, we present an inverse-designed approach for the precise correction of CVD. The wavelength shift of a patient's abnormal cone photoreceptors was measured to inversely design the best blocking wavelength and blocking rate of the lens. Then the customized aid lenses were fabricated using silica-coated gold nanoparticles with appropriate sizes and concentrations, verified by the simulated color vision and human tests. This study demonstrates the potential of the inverse-designed aid lenses in precise color filtering and customized CVD management.

Topics & Concepts

Lens (geology)Blocking (statistics)Color visionMaterials scienceInverseComputer scienceOpticsArtificial intelligenceMathematicsPhysicsComputer networkGeometryOcular Surface and Contact LensColor Science and ApplicationsOphthalmology and Visual Impairment Studies
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