Peganum harmala L. seed extract attenuates anxiety and depression in rats by reducing neuroinflammation and restoring the BDNF/TrkB signaling pathway and monoamines after exposure to chronic unpredictable mild stress
Yasemin Tekşen, Meliha Koldemir Gündüz, Derya Berikten, Fikriye Yasemin Özatik, Hasan Emre Aydın
Topics & Concepts
Peganum harmalaHarmalineMonoamine neurotransmitterBehavioural despair testHarminePharmacologyElevated plus mazeEndocrinologyInternal medicineChemistrySerotoninMedicineAntidepressantTraditional medicineHippocampusPsychiatryAnxietyReceptorSynthesis and bioactivity of alkaloidsTryptophan and brain disordersBioactive Compounds and Antitumor Agents