Spatial modulation of visual responses arises in cortex with active navigation
E. Mika Diamanti, Charu Bai Reddy, Sylvia Schröder, Tomaso Muzzu, Kenneth D. Harris, Aman B. Saleem, Matteo Carandini
Abstract
During navigation, the visual responses of neurons in mouse primary visual cortex (V1) are modulated by the animal's spatial position. Here we show that this spatial modulation is similarly present across multiple higher visual areas but negligible in the main thalamic pathway into V1. Similar to hippocampus, spatial modulation in visual cortex strengthens with experience and with active behavior. Active navigation in a familiar environment, therefore, enhances the spatial modulation of visual signals starting in the cortex.
Topics & Concepts
Visual cortexNeuroscienceSpatial memoryModulation (music)Spatial modulationOrientation columnCortex (anatomy)HippocampusPsychologyBiologyPhysicsComputer scienceCognitionStriate cortexWorking memoryAcousticsMIMOComputer networkChannel (broadcasting)Neuroscience and Neuropharmacology ResearchNeural dynamics and brain functionMemory and Neural Mechanisms