Structural Reassignment of Two Polyenol Natural Products
Andrei G. Kutateladze, Roderick W. Bates, Mikhail Elyashberg, Craig M. Williams
Abstract
Abstract Unusual polyenols that defied chemical principles were reassigned as the nucleosides, adenosine and uridine, using a combination of chemical intuition underpinned by Computer Assisted Structure Elucidation (CASE) and DFT methods.
Topics & Concepts
ChemistryUridineIntuitionStereochemistryComputational chemistryEpistemologyBiochemistryRNAPhilosophyGeneMolecular spectroscopy and chiralityMicrobial Natural Products and BiosynthesisCarbohydrate Chemistry and Synthesis