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Pegfilgrastim (PEG-G-CSF) induces anti-PEG IgM in a dose dependent manner and causes the accelerated blood clearance (ABC) phenomenon upon repeated administration in mice

Nehal E. Elsadek, Amr S. Abu Lila, Sherif E. Emam, Taro Shimizu, Haruka Takata, Hidenori Ando, Yu Ishima, Tatsuhiro Ishida

2020European Journal of Pharmaceutics and Biopharmaceutics42 citationsDOI

Topics & Concepts

PegfilgrastimFilgrastimGranulocyte colony-stimulating factorPEG ratioPharmacologyNeutropeniaMedicineChemotherapyImmunologyChemistryInternal medicineFinanceEconomicsNeutropenia and Cancer InfectionsBlood disorders and treatmentsHematopoietic Stem Cell Transplantation
Pegfilgrastim (PEG-G-CSF) induces anti-PEG IgM in a dose dependent manner and causes the accelerated blood clearance (ABC) phenomenon upon repeated administration in mice | Litcius