Resveratrol drives cancer cell senescence <i>via</i> enhancing p38MAPK and DLC1 expressions
Yan Bian, Xingjie Wang, Zhaodi Zheng, Guanghui Ren, Hongyan Zhu, Mengxue Qiao, Guorong Li
Abstract
activating ER-stress through the SIRT1/p38MAPK and NO/DLC1 pathways provide a solid base for its clinical application and its preventive application as a food additive.
Topics & Concepts
ResveratrolSenescenceCancerCellCancer cellCancer researchCell biologyDNA damageChemistryBiologyPharmacologyBiochemistryDNAGeneticsSirtuins and Resveratrol in MedicineTelomeres, Telomerase, and SenescenceRedox biology and oxidative stress