A chemical derivatization-based pseudotargeted liquid chromatography-tandem mass spectrometry method for sensitive and high coverage determination of bile acids in human serum
Xin Xiong, Xunke Gu, Xiaona Li, Keke Jia, Yuan Wei, Rongsheng Zhao
Topics & Concepts
ChemistryChromatographyDerivatizationTandem mass spectrometryReagentSelected reaction monitoringIon suppression in liquid chromatography–mass spectrometryGlucuronic acidLiquid chromatography–mass spectrometryHigh-performance liquid chromatographyMass spectrometryBiochemistryOrganic chemistryPolysaccharideDrug Transport and Resistance MechanismsLiver Disease Diagnosis and TreatmentPediatric Hepatobiliary Diseases and Treatments