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mTORC1 activation contributes to autophagy inhibition via its recruitment to lysosomes and consequent lysosomal dysfunction in cadmium-exposed rat proximal tubular cells

Cai-Yu Lian, Heng Yang, Zhenzhen Zhai, Zifa Li, Diangang Han, Lin Wang

2020Journal of Inorganic Biochemistry27 citationsDOI

Topics & Concepts

AutophagymTORC1LysosomeCell biologyChemistryBafilomycinVacuoleBiochemistryBiologySignal transductionPI3K/AKT/mTOR pathwayApoptosisEnzymeCytoplasmAutophagy in Disease and TherapyCannabis and Cannabinoid ResearchHeavy Metal Exposure and Toxicity
mTORC1 activation contributes to autophagy inhibition via its recruitment to lysosomes and consequent lysosomal dysfunction in cadmium-exposed rat proximal tubular cells | Litcius