Flavone inspired discovery of benzylidenebenzofuran-3(2H)-ones (aurones) as potent inhibitors of human protein kinase CK2
Mykola Protopopov, Vasyl Vdovin, Sergiy A. Starosyla, Iryna Borysenko, A.O. Prykhod'ko, С. С. Лукашов, Yaroslav V. Bilokin, Volodymyr G. Bdzhola, S. M. Yarmoluk
Topics & Concepts
ChemistryFlavonesStructure–activity relationshipStereochemistryCombinatorial chemistryIn vitroBiochemistryChromatographySynthesis of Organic CompoundsSynthesis and biological activityProtein Kinase Regulation and GTPase Signaling