Litcius/Paper detail

GERD: A practical approach

Andrew Young, Mythri Anil Kumar, Prashanthi N. Thota

2020Cleveland Clinic Journal of Medicine69 citationsDOIOpen Access PDF

Abstract

Gastroesophageal reflux disease (GERD) is mainly a clinical diagnosis based on typical symptoms of heartburn and acid regurgitation. Current guidelines indicate that patients with typical symptoms should first try a proton pump inhibitor (PPI). If reflux symptoms persist after 8 weeks on a PPI, endoscopy of the esophagus is recommended, with biopsies taken to rule out eosinophilic esophagitis. This review discusses the evidence for different medical, endoscopic, and surgical therapies and presents a management algorithm.

Topics & Concepts

MedicineGERDHeartburnEosinophilic esophagitisRegurgitation (circulation)Proton-pump inhibitorGastroenterologyRefluxInternal medicineEsophagusEndoscopyDiseaseEsophagitisGeneral surgeryGastroesophageal reflux and treatmentsEosinophilic EsophagitisHelicobacter pylori-related gastroenterology studies