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Harada-like syndrome post-Covishield vaccination: A rare adverse effect

Y. N. K. Reddy, Anamika Pandey, Ayushi Ojha, Suresh Ramchandani

2021Indian Journal of Ophthalmology13 citationsDOIOpen Access PDF

Abstract

Covishield is in wide use in India with about 80% efficacy. Serious side effects are still under study. A 30-year-old female presented to us 7 days post-vaccination with a 5-day history of sudden diminution of vision in both eyes. The clinical findings were suggestive of the Vogt-Koyanagi-Harada (VKH) syndrome. She was treated with high-dose oral steroids. At this juncture, the association was unclear. However, it was justified by an acute flare-up of uveitis on day 2 post the second dose of vaccination despite ongoing steroids. A direct correlation of Harada-like syndrome with the Covishield vaccine is observed here.

Topics & Concepts

MedicineVaccinationUveitisAdverse effectVogt–Koyanagi–Harada diseaseDermatologyPediatricsOphthalmologyInternal medicineImmunologyOcular Diseases and Behçet’s SyndromeRetinal and Optic ConditionsSystemic Lupus Erythematosus Research
Harada-like syndrome post-Covishield vaccination: A rare adverse effect | Litcius