Asymmetric Catalytic Transformations of Aza‐<i>ortho</i>‐ and Aza‐<i>para</i>‐Quinone Methides
Mercedes Zurro, Aitor Maestro
Abstract
Abstract The catalytic methodologies for the derivatization of aza‐QM have recently appeared in the literature and involve organocatalytic and organometallic approaches. This review aims at analyzing the diverse catalytic systems involving chiral NHC carbenes, phosphoric acids, phosphoramidites, phosphine and copper and palladium catalysis showing its applicability for the synthesis of a diverse away of N ‐containing compounds which in many cases have biological activity.
Topics & Concepts
PhosphineCatalysisChemistryDerivatizationPalladiumQuinoneCombinatorial chemistryCopperOrganic chemistryPhosphoric acidHigh-performance liquid chromatographySynthesis of Indole DerivativesAxial and Atropisomeric Chirality SynthesisCarbohydrate Chemistry and Synthesis