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Dp44mT, an iron chelator, suppresses growth and induces apoptosis via RORA-mediated NDRG2-IL6/JAK2/STAT3 signaling in glioma

Jinpeng Zhou, Yang Jiang, Junshuang Zhao, Haiying Zhang, Jinlong Fu, Peng Luo, Yanju Ma, Dan Zou, Huiling Gao, Jiangfeng Hu, Ye Zhang, Zhitao Jing

2020Cellular Oncology61 citationsDOIOpen Access PDF

Topics & Concepts

STAT proteinGliomaSTAT3Chromatin immunoprecipitationCancer researchJanus kinase 2ChemistryApoptosisSignal transductionCell growthTUNEL assayBiologyCell biologyGene expressionPromoterBiochemistryGeneMechanisms of cancer metastasisChromatin Remodeling and CancerCancer Mechanisms and Therapy