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Platinum complexes inhibit HER-2 enriched and triple-negative breast cancer cells metabolism to suppress growth, stemness and migration by targeting PKM/LDHA and CCND1/BCL2/ATG3 signaling pathways

Xue Bai, Amjad Ali, Zhimin Lv, Na Wang, Xing Zhao, Huifang Hao, Yongmin Zhang, Faiz‐Ur Rahman

2021European Journal of Medicinal Chemistry36 citationsDOI

Topics & Concepts

SKBR3ChemistryCancer researchTriple-negative breast cancerCancer cellBreast cancerClonogenic assayCancerCell growthMCF-7CellBiochemistryBiologyInternal medicineMedicineHuman breastMetal complexes synthesis and propertiesFerrocene Chemistry and ApplicationsClick Chemistry and Applications
Platinum complexes inhibit HER-2 enriched and triple-negative breast cancer cells metabolism to suppress growth, stemness and migration by targeting PKM/LDHA and CCND1/BCL2/ATG3 signaling pathways | Litcius