Lidocaine Alleviates Neuropathic Pain and Neuroinflammation by Inhibiting HMGB1 Expression to Mediate MIP-1α/CCR1 Pathway
Mingming Li, Hao Jiang, Kuo Gu, Xuechao Sun, Jing Gu, Chunming Li, Guonian Wang
Topics & Concepts
SNiNeuropathic painHMGB1MedicineBlotCCR1TUNEL assayPharmacologyNerve injuryWestern blotChemokineChemistryAnesthesiaChemokine receptorReceptorInternal medicineImmunohistochemistryBiochemistryHydrolysisGeneAcid hydrolysisPain Mechanisms and TreatmentsNeuropeptides and Animal PhysiologyNeuroinflammation and Neurodegeneration Mechanisms