Safety, PK/PD and preliminary anti-tumor activities of pegylated recombinant human arginase 1 (BCT-100) in patients with advanced arginine auxotrophic tumors
Paul Cheng, Angela M. Liu, Alberto Bessudo, Francis Mussai
Topics & Concepts
MedicinePharmacokineticsArgininePharmacodynamicsCohortAdverse effectInternal medicinePharmacologyPopulationGastroenterologyUrologyChemistryAmino acidBiochemistryEnvironmental healthCancer Research and TreatmentsVirus-based gene therapy researchCancer, Hypoxia, and Metabolism