Germline PTEN genotype-dependent phenotypic divergence during the early neural developmental process of forebrain organoids
Shin Chung Kang, Nick Sarn, Juan Venegas, Zhibing Tan, Masahiro Hitomi, Charis Eng
Topics & Concepts
PTENBiologyOrganoidHaploinsufficiencyGermlineGeneticsCancer researchPI3K/AKT/mTOR pathwayPhenotypeGeneSignal transductionCRISPR and Genetic EngineeringPluripotent Stem Cells ResearchPI3K/AKT/mTOR signaling in cancer