Nanomaterial-based delivery vehicles for therapeutic cancer vaccine development
Jie Liang, Xiao Zhao
Abstract
tools, neoantigen-based therapeutic vaccines might become potent personalized vaccines for tumor treatments. In this review, we summarize the development of preclinical therapeutic cancer vaccines and the advancements of nanomaterial-based delivery vehicles for cancer immunotherapies, which provide the basis for a personalized vaccine delivery platform. Moreover, we review the existing challenges and future perspectives of nanomaterial-based personalized vaccines for novel tumor immunotherapies.
Topics & Concepts
ImmunogenicityCancer vaccineImmune systemImmunotherapyCancer immunotherapyMedicineCancerImmunologyInternal medicineImmunotherapy and Immune ResponsesRNA Interference and Gene Deliveryvaccines and immunoinformatics approaches